As a drummer, I deal with the exact same principles in my playing. I learned to play a certain way from when I was 9 years old, right hand for fast rhythm metronome type stuff (hi-hats, ride cymbals, etc.) and left hand for the back beat (snare drum) - right foot for pounding out the downbeat and left foot for holding down the hi-hat and changing the sound through lifting the foot, not pushing down.
I worked hard at that format and at a certain age realized I had vastly exceeded every possible limitation I had envisioned for myself using that playing style. So, to challenge myself, at age 17 I tried to swap how I used my hands a feet and develop other means of playing the kit. It was much harder to get it when I attempted to flip it around, but time and hard work won me over, but I couldn't quickly switch between the two. I could perform a rhythm one way, but then I'd have to stop and clear my head before I could perform the same rhythm the other way around. So, I worked on that, it took even longer. By the time I was 22 I could on the fly swap between playing right handed and playing left handed. However, my skills at playing left handed were nowhere close to what I was capable of if playing right handed.
So, I get what this is about - crazy stuff.