Not sure... the idea behind Harrison Ford's character is that he is questioning whether he is a replicant or not. We now know he was a replicant from interviews Scott has done. So, perhaps a story line which has Ford learning more, researching more, and reacting to the reality of what he is while at the same time still hunting rebel "old style" replicants would be fascinating.
Not in the original (theatrical release) movie. R. Scott wanted to change the story into Deckard being a replicant and did his Director's Cut which deleted and added a few things. The result wasn't as successful as he has hoped for so some years later, he produced Final Cut. IMO, it's still not successful due to rearranging of already established (& made movie) story.